INVESTIGATORS

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H. Richard Adams, DVM, PhD Professor Department of Veterinary Physiology and Pharmacology 979-845-5053 radams@cvm.tamu.edu		Circulatory shock; myocardial and vascular dysfunction in endotoxemia; role of nitric oxide in vasoregulation.
Gianfranco D. Alpini, PhD Professor Department of Internal Medicine 254-742-7044 galpini@tamu.edu		Functional heterogeneity of the intrahepatic biliary tree; hormonal, cholinergic, and adrenergic regulation of secretory and proliferative processes.
Kenneth M. Baker, MD Professor Department of Internal Medicine 254-743-2763 kbaker@medicine.tamhsc.edu		Signaling pathways in cardiac myocytes; mechanisms of cardiac cell growth; angiotensin and cardiac hypertrophy.
Kayla J. Bayless, PhD Assistant Professor Department of Molecular and Cellular Medicine Lab: 979-845-7287 Office: 979-845-7205 kbayless@medicine.tamhsc.edu		Molecular signals that regulate endothelial cell invasion in three-dimensional matrices; ocular angiogenesis.
Gregory J. Bix, MD, PhD Assistant Professor Department of Molecular and Cellular Medicine 979-862-7613 gjbix@medicine.tamhsc.edu		vascular matrix biology, stroke
George W. Booz, PhD Assistant Professor Department of Internal Medicine 254-743-0384 gbooz@medicine.tamhsc.edu		Angiotensin II signaling in cardiac cells.
Clifford J. Buckley, MD Professor Department of Surgery 254-724-5975 cbuckley@swmail.sw.org		Peripheral vascular disease; intravascular ultrasonography; quality/cost control issues in practice of vascular surgery.
Ed W. Childs, MD Associate Professor Department of Surgery 254-724-5638 ewchilds@medicine.tamhsc.edu		Hemorrhagic shock; microvascular permeability; leukocyte/endothelial interactions; oxygen radicals and PAF in microvascular dysfunction.
Demetra D. Christou, PhD Assistant Professor Department of Health and Kinesiology 979-862-3090 ddchristou@hlkn.tamu.edu		Obesity, aging, exercise and human cardiovascular performance.
Gerard L Cote, PhD Professor Department of Biomedical Engineering 979-845-4196 cote@tamu.edu		Optical sensing and spectroscopy, optical diagnostics, biomedical imaging, development of non-invasive sensors
John C. Criscione, MD, PhD Assistant Professor Department of Biomedical Engineering 979-845-5428 jccriscione@tamu.edu		Cardiac mechanics; constitutive mechanics; computational mechanics; cellular mechanics.
Stephen F. Crouse, PhD Professor Kinesiology Division Department of Health and Kinesiology 979-845-3997 s-crouse@tamu.edu		Cardiovascular risk factors; blood lipid profiles in sedentary and exercising subjects.
Timothy A. Cudd, DVM, PhD Associate Professor Department of Veterinary Physiology and Pharmacology 979-862-1972 t-cudd1@tamu.edu		Reflex control of cardiovascular and endocrine systems in the adult and the fetus
Gregory J. Dehmer, MD Professor Department of Internal Medicine 254-724-6713 gdehmer@swmail.sw.org		Platelets, thrombosis and myocardial infarction; national standards for interventional cardiology practice and training.
David E. Dostal, PhD Associate Professor Department of Internal Medicine 254-743-2464 ddostal@medicine.tamhsc.edu		Regulation and functional role of the cardiac renin-angiotensin system.
Theresa W. Fossum, DVM, PhD Professor Department of Small Animal Medicine and Surgery 979-845-2351 t-fossum@tamu.edu		Cardiovascular surger; animal models of cardiovascular disease; chylothorax; lymphatic system; evaluation of artificial heart performance.
Arthur E. Frankel, MD Professor Department of Internal Medicine 254-724-2111 afrankel@swmail.sw.org		Preclinical and clinical evaluation of recombinant peptide toxins: vascular leak syndrome (VLS) associated with exposure to circulating peptide toxins in vivo; effects of anthrax toxins on the animal and human cardiovascular system; and targeting peptide toxins to tumor vasculature.
Anatoliy A. Gashev, MD, PhD Research Associate Professor Department of Systems Biology and Translational Medicine 254-742-7147 gashev@tamu.edu		Lymphatic physiology, mechanisms of lymphatic pumping, behavior of human lymphatics.
Harris J. Granger, PhD Distinguished Professor Department of Systems Biology and Translational Medicine 254-742-7033 granger@tamu.edu		Angiogenesis; microvascular permeability; growth factor signaling; genomics; computer simulation of biological processes.
Mariah Hahn, PhD Assistant Professor Department of Chemical Engineering 979-845-3361 mariah.hahn@che.tamu.edu		Cell-cell and cell-material interactions at a fundamental level; controlling material, mechanical, and chemical properties at the microscale; vocal fold regeneration; vascular tissue engineering
Cristine L. Heaps, PhD Assistant Professor Department of Veterinary Physiology & Pharmacology 979-458-0753 cheaps@cvm.tamu.edu		Cellular and functional adaptations in the coronary circulation in response to coronary artery disease and exercise training; specifically the adaptive responses of both smooth muscle ion channels and endothelial nitric oxide regulation in the regulation of coronary artery function with disease and exercise training.
Travis W. Hein, PhD Assistant Professor Department of Surgery 254-724-3550 thein@tamu.edu		Physiology and pathophysiology of coronary and retinal microcirculation; metabolic regulation of microvascular blood flow; nitric oxide and microvascular function; influence of antioxidants/oxidative stress on microvascular vasomotor function
R. Kelly Hester, PhD Professor Department of Systems Biology and Translational Medicine 979-862-4900 hester@medicine.tamhsc.edu		Cardiovascular pharmacology; vascular smooth muscle; excitation-contraction coupling
Hung-Chung (Joe) Huang, MT, MS , PhD Assistant Research Scientist Department of Systems Biology and Translational Medicine 254-742-7176 hc.jhuang@tamu.edu		Computational biochemistry; bioinformatics; data mining & pattern discovery; microarray analysis & biomarker discovery; non-coding RNAs; molecular dynamics simulations; in silico drug design
Jay D. Humphrey, PhD Professor Department of Biomedical Engineering 979-845-5558 jhumphrey@tamu.edu		Cardiovascular mechanics; engineering analysis of vascular remodeling and growth in hypertension; mechanics of aneurysms.
Wonmuk Hwang, PhD Assistant Professor Department of Biomedical Engineering 979-458-0178 hwm@tamu.edu		Computer simulation and theoretical modeling of biomolecular self-assembly and mechanics; amyloid fibrillogenesis; biofilament mechanics; collagen dynamics; cytoskeletal mechanics; kinesin motility; molecular motors
Roland Kaunas, PhD Assistant Professor Department of Biomedical Engineering 979-845-2412 rkaunas@bme.tamu.edu		Mechanical properties of cells; regulation of mechanotransduction via cytoskeletal reorganization; angiogenesis; cell-matrix interactions.
Rajesh Kumar, PhD Assistant Professor Department of Internal Medicine 254-743-1203 kumar@medicine.tamhsc.edu		Regulation of gene expression in cardiac hypertrophy, transcription factors, cluster analysis of genomic responses.
Lih Kuo, PhD Professor Department of Systems Biology and Translational Medicine 254-742-7041 lkuo@tamu.edu		Regulation of coronary microvascular function; endothelium and vascular smooth-muscle biology; atherosclerosis and ischemia-reperfusion injury.
Glen A. Laine, PhD Professor Department of Veterinary Physiology and Pharmacology 979-845-7261 glaine@tamu.edu		Microvascular, interstitial and lymphatic interactions in regulating myocardial fluid balance; myocardial edema and fibrosis; left ventricular mechanics.
Zhenbo Li, MD Assistant Research Scientist Department of Systems Biology and Translational Medicine 254-724-6314 zhenboli@tamu.edu		Reneovascularization of ischemic tissues and hypertensive myocardial hypertrophy, using adenovirus vector, to explore the signal transduction pathway
Mingyao Liu, PhD Associate Professor IBT Center for Cancer Biology and Nutrition 713-677-7505 (office) 713-677-7535 (lab) mliu@ibt.tamhsc.edu		G-protein signaling of cell growth, differentiation and apoptosis; vascular smooth muscle contraction
Ronald D. MacFarlane, PhD Professor Department of Chemistry 979-845-2021 macfarlane@mail.chem.tamu.edu		Application of ionization mass spectrometry and capillary electrophoresis to problems related to human medicine; lipoprotein profiling and coronary vascular disease.
James F. Martin, PhD Professor Center for Cancer Biology and Nutrition 713-677-7558 jmartin@ibt.tamhsc.edu		Homeobox genes; vertebrate embryogenesis; cardiac development; mouse genetics.
Michael P. Massett, PhD Assistant Professor Department of Health and Kinesiology 979-862-4687 mmassett@hlkn.tamu.edu		Genomic/genetic approaches to identify genes associated with exercise training, physiological adaptations to exercise training as they relate to markers of chronic disease, endothelial function, vascular remodeling
Steven A. Maxwell, PhD Associate Professor Department of Molecular and Cellular Medicine 979-845-7206 s-maxwell@tamu.edu		Cancer; oncogenes; tumor suppressor genes; apoptosis; angiogenesis.
Wallace McKeehan, PhD Professor IBT Center for Cancer Biology and Nutrition 713-677-7522 wmckeehan@ibt.tamhsc.edu		Molecular signaling through fibroblast growth factor and transforming growth factors, prostate cancer, cardiovascular diseases, liver regeneration, plant products for the prevention and treatment of cancer
Catherine McNeal, MD, PhD Assistant Professor Department of Internal Medicine 254-724-9799 cmcneal@swmail.sw.org		Lipid profiling using mass spectrometry and capillary electrophoresis; hypercholesterolemia in children.
Cynthia J. Meininger, PhD Professor Department of Systems Biology and Translational Medicine 254-742-7037 cjm@tamu.edu		Physiologic control of angiogenesis; vascular complications in diabetes; nitric oxide production and proliferation of endothelial cells; mast cell modulation of tumor angiogenesis.
Matthew M. Miller, DVM Professor Department of Veterinary Small Animal Medicine and Surgery 979-845-2351 m-miller36622@tamu.edu		Cardiomyopathies; color Doppler ultrasonography
Brett M. Mitchell, PhD Assistant Professor Department of Internal Medicine 254-724-6267 bmitchell@medicine.tamhsc.edu		Endothelial cell and vascular biology; regulation of arterial blood pressure; role of intracellular calcium and nitric oxide in hypertension caused by immunosuppressive drugs and pregnancy; transgenic mouse models of hypertension
James E. Moore, Jr., PhD Associate Professor Department of Biomedical Engineering 979-845-3299 jmoorejr@tamu.edu		Cardiovascular mechanics, hemodynamics, restenosis, stents
Mariappan Muthuchamy, PhD Associate Professor Department of Systems Biology and Translational Medicine 979-847-9251 marim@tamu.edu		Structure and function relationship of contractile proteins - a transgenic approach; molecular and physiological mechanisms of cardiac muscle contraction.
Jing Pan, MD, PhD Assistant Professor Department of Internal Medicine 254-743-2461 jpan@medicine.tamhsc.edu		Role of rho, MAP kinases and PKC isoforms in cardiac hypertrophy retinoids, glycogen synthase kinase, and the dual-specificity phosphatase MKP-1 as negative modulators of cardiomyocyte hypertrophy
Janet L. Parker, PhD Professor Department of Systems Biology and Translational Medicine 979-458-1033 jlp@tamu.edu		Chronic coronary occlusion and collateral development; exercise training; vascular dysfunction in shock and sepsis.
Alan R. Parrish, PhD Associate Professor Department of Systems Biology and Translational Medicine 979-458-1538 parrish@medicine.tamhsc.edu		Acute renal failure; regulation of cadherin/catenin complexes; increased susceptibility to injury in aging kidney
Xu Peng, MD, PhD Assistant Professor Department of Systems Biology and Translational Medicine 254-742-7033 xpeng@medicine.tamhsc.edu		Cardiac and vascular development; angiogenesis and vasculogenesis
Thomas V. Peterson, PhD Professor Department of Systems Biology and Translational Medicine 979-845-7483 tvp@tamu.edu		Neural and hormonal control of blood volume and renal function
Christopher M. Quick, PhD Associate Professor Department of Veterinary Physiology and Pharmacology 979-845-2645 cquick@tamu.edu		Quantitative cardiovascular physiology; cardiovascular remodeling and simulation; arterial hemodynamics and pulse wave phenomena
J. James Rohack, MD Professor Department of Internal Medicine 254-724-5593 jrohack@swmail.sw.org		Cardiovascular performance in exercising humans; blood lipids and lipoproteins in exercising males and females.
Robert H. Rosa, Jr., MD Associate Professor Department of Surgery 254-724-5541 rrosa@swmail.sw.org		Retinal vasoregulation; retinal and choroidal neovascularization; macular degeneration, diabetic retinopathy
H. Wayne Sampson, PhD Professor Department of Systems Biology and Translational Medicine 979-774-5680 sampson@medicine.tamhsc.edu		Bone biology; genomic responses to bone injury; laser capture microdissection
Robert C. Scott, III, M.D., Ph.D. Assistant Professor of Medicine Department of Internal Medicine 254-724-7286 rcscott@swmail.sw.org		Mechanisms of cardiac hypertrophy and cardiomyopathies; myocarditis; renin-angiotensin-aldosterone system in cardiovascular disease; endothelial function/mechanisms of dysfunction; mechanisms of atherogenesis; evaluation and manipulation of endogenous cardiac stem cells.
Rajat Sethi, PhD Assistant Professor Department of Pharmaceutical Sciences Irma Lerma Rangel College of Pharmacy Kingsville 361-593-4275 kfrs002@tamuk.edu		Cardiac signal transduction in ischemia/reperfusion injury, myocardial ischemia, heart failure, hypertension and diabetes using Langendorff isolated rat heart preparation, cardiac myocytes as well as in-vivo models of heart failure.
Avadhesh C. Sharma, PharMD, PhD Associate Professor Department of Biomedical Sciences Baylor College of Dentistry 214-828-8303 ASharma@bcd.tamhsc.edu		Sepsis-induced myocardial dysfunction, in vivo and in vitro paradigms, apoptosis and signaling cascade
John N. Stallone, PhD Associate Professor Department of Veterinary Physiology and Pharmacology 979-862-3065 jstallone@cvm.tamu.edu		Humoral interactions between vascular smooth muscle and endothelium; genomic and non-genomic effects of gonadal steroid hormones on vascular function.
Randolph Stewart, DVM, PhD Assistant Professor Department of Veterinary Physiology and Pharmacology 979-862-7764 r-230@tamu.edu		Lymphatic function; microvascular and interstitial fluid dynamics; synovial fluid balance; cardiac function.
George Stoica, DVM, PhD Professor Department of Veterinary Pathobiology 979-845-5089 gstoica@cvm.tamu.edu		Cancer biology; growth factors; tumor angiogenesis; immunohistochemical analysis of peripheral arteries after balloon angioplasty.
Andreea Trache, PhD Assistant Professor Department of Systems Biology and Translational Medicine 979-845-7990 trache@tamu.edu		Development and integration of novel microscopy techniques applied to monitoring molecular dynamics in live cells
Jerome P. Trzeciakowski, PhD Professor Department of Systems Biology and Translational Medicine 979-845-2847 jpt@tamu.edu		Biomathematics; nonlinear dynamics, signal processing techniques and time series analysis; theoretical analysis of signal transduction mechanisms; chaotic mapping and genomic patterns.
Vincent VanBuren, PhD Assistant Professor Department of Systems Biology and Translational Medicine 512-970-2057 vanburen@tamu.edu		Biocomputing; biological network reconstruction from high-throughput data; microarray analysis; Monte Carlo simulations; biological sequence analysis
Fen Wang, PhD Assistant Professor Center for Cancer Biology and Nutrition Institute of Biosciences and Technology 713-677-7520 fwang@ibt.tamhsc.edu		The role of fibroblast growth factor (FGF) and FGF receptor (FGFR) in liver, cardiovascular, wound healing and prostate disease.
Jeremy S. Wasser, PhD Associate Professor Department of Veterinary Physiology and Pharmacology 979-862-4655 j-wasser@tamu.edu		Comparative cardiovascular physiology; biological applications of magnetic resonance spectroscopy; mechanisms of hypoxia tolerance in turtle heart.
Emily Wilson, PhD Associate Professor Department of Systems Biology and Translational Medicine 979-862-8673 emilyw@tamu.edu		Mechanical forces as regulators of smooth-muscle phenotype; signal transduction through integrin-extracellular matrix system; regulation of integrin expression in endothelial cells.
Christopher R. Woodman, PhD Assistant Professor Department of Health and Kinesiology 979-845-0515 woodmanc@hlkn.tamu.edu		Vascular physiology, exercise physiology; interactive effects of aging and exercise training on skeletal muscle vascular beds; adaptation of endothelial and vascular smooth muscle cells to aging
Steven M. Wright, PhD Professor Department of Electrical Engineering 979-845-9413 wright@ee.tamu.edu		Theory and application of array coils in magnetic resonance spectroscopy; NMR spectroscopy for monitoring cardiac energetics in vivo.
Guoyao Wu, PhD Profesor Department of Animal Science 979-845-2714 g-wu@tamu.edu		Arginine metabolism and vascular function; regulation of vascular cell proliferation by nitric oxide, glutamine, and polyamines.
Xin Wu, MD Research Assistant Professor Department of Systems Biology and Translational Medicine 979-845-9771 xinwu@tamu.edu		Functional studies in cardiovascular system using electrophysiology, atomic force microscopy, immunofluorescence and force measurements etc; integrin-dependent regulation of ion channels; mechanosensitive ion channels.
David C. Zawieja, PhD Professor Department of Systems Biology and Translational Medicine 254-231-1500 dcz@tamu.edu		Microvascular exchange; lymphatic microcirculation; lymphangiogenesis; regulation of calcium within vascular cells.
Warren E. Zimmer, PhD Professor Department of Systems Biology and Translational Medicine 979-845-2896 wezimmer@medicine.tamhsc.edu		Smooth muscle differentiation; gene expression and transcription factors; transgenic mouse models; stem cell biology

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